A condition known as post-orgasmic illness syndrome (POIS) has been documented among men since 2002, according to a report from the Los Angeles Times on 17 January.
Men who have POIS experience feverishness, runny nose, extreme fatigue and burning eyes that may last for seven days.
Whereas some physicians think that the syndrome is psychosomatic in nature or is influenced by the mind and emotions, Dutch scientists do not think so.
In two publications in the Journal of Sexual Medicine, Marcel D. Waldinger of the Utrecht University in the Netherlands showed that the disorder is caused by allergy and that it is possible to desensitize men with the health problem.
Of the 45 men with POIS, 33 agreed to be desensitized using the standard skin-prick allergy test using the diluted form of their own ejaculate.
Of the 33, Waldinger's team demonstrated that 29 (88%) had positive reaction to the test, an indication of autoimmune response.
However, the researchers said that it was not clear why they became symptomatic only when they ejaculated. The men did not experience being sick when they masturbated but did not release the semen.
Waldinger told Reuters, "They didn't feel ill when they masturbated without ejaculating. But as soon as the semen came from the testes ... after that, they became ill, sometimes within just a few minutes."
In another study, two men underwent hyposensitization therapy through injections of dilute semen going up to more concentrated forms over a period of months. After 12 and 36 months, the research group reported that the men had significant decrease of POIS symptoms.